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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYRK2
All Species:
0
Human Site:
S129
Identified Species:
0
UniProt:
Q92630
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92630
NP_003574.1
601
66652
S129
V
P
E
R
Q
L
D
S
I
H
R
R
Q
G
S
Chimpanzee
Pan troglodytes
XP_509205
601
66595
Rhesus Macaque
Macaca mulatta
XP_001117134
601
66643
Dog
Lupus familis
XP_538273
601
66656
Cat
Felis silvestris
Mouse
Mus musculus
Q5U4C9
599
66538
Rat
Rattus norvegicus
Q4V8A3
586
65492
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511087
546
60615
Chicken
Gallus gallus
Q5ZIU3
526
59419
Frog
Xenopus laevis
NP_001088793
567
63329
Zebra Danio
Brachydanio rerio
NP_001038298
587
65453
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83102
828
92722
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023208
796
87422
Sea Urchin
Strong. purpuratus
XP_799140
561
63192
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51566
467
54180
Baker's Yeast
Sacchar. cerevisiae
P14680
807
91227
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.6
98.3
N.A.
97
59.7
N.A.
78.6
81.3
64.5
83.6
N.A.
43.3
N.A.
45.7
63.7
Protein Similarity:
100
98.8
99.8
99
N.A.
98.5
71.8
N.A.
83
84.5
75
89.8
N.A.
54.9
N.A.
55.6
73.5
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
N.A.
0
0
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
0
0
0
0
N.A.
0
N.A.
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
27.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.6
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
100
0
0
0
0
0
0
0
100
0
0
% Q
% Arg:
0
0
0
100
0
0
0
0
0
0
100
100
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
100
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _